UBC 150
Ursodeoxycholic Acid Tablets IP 150 mgMARKETER: Syngex Pharma Pvt Ltd
USES OF UBC 150 TABLET
- Treatment of Gall stones, primary biliary cholangitis and biliary and liver diseases caused by cystic fibrosis.
HOW UBC 150 TABLET WORKS
UBC 150 Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. It belongs to a group of medicines called the biliary agent or gallstone dissolution agents used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile children above 6 years with biliary and liver diseases caused by cystic fibrosis. UBC 150 Tablet breaks down the cholesterol that has formed into gall bladder stones, thereby dissolving the stones. UBC 150 Tablet has a protective effect on the liver cells and the immune system, thereby improving liver function. UBC 150 Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, UBC 150 Tablet increases the bile flow.
INTRODUCTION ABOUT UBC 150 TABLET
UBC 150 Tablet belongs to a group of medicines called biliary agents or gallstone dissolution agents. These agents are used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in the bile, and children above 6 years old with biliary and liver diseases caused by cystic fibrosis.
UBC 150 Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. UBC 150 Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gallbladder stones composed mainly of cholesterol. UBC 150 Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.
Take UBC 150 Tablet with food. You are advised to take UBC 150 Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor before taking UBC 150 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Do not take UBC 150 Tablet if you are pregnant or breastfeeding unless prescribed. UBC 150 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with UBC 150 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.
DIRECTIONS FOR USE
Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use.Dispersible tablet: Disperse the tablet in water and consume it.
SIDE EFFECTS OF UBC 150 TABLET
COMMON SIDE EFFECTS:
Abdominal discomfort
Abdominal pain
Diarrhoea
Nausea
Fever
Cough
Rash
Dizziness
Indigestion
Black or tarry stools
Frequent and painful urination
Weakness
WARNING & PRECAUTIONS
Drug Warnings
Do not take UBC 150 Tablet if you are allergic to any of its contents, if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking UBC 150 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking UBC 150 Tablet with other medicines as UBC 150 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Do not take UBC 150 Tablet if you are pregnant or breastfeeding unless prescribed. UBC 150 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with UBC 150 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.
Drug Interactions
Drug-Drug Interactions: UBC 150 Tablet may interact with antibiotics (ciprofloxacin and dapsone), antihypertensive agents (nitrendipine), immunosuppressants (cyclosporine), hormones (oestrogen), and antacids (aluminium hydroxide, aluminium carbonate, magaldrate).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have biliary obstruction and liver impairment, variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), or liver encephalopathy.
Drug-Drug Interactions Checker List
CIPROFLOXACIN
DAPSONE
CYCLOSPORINE
ESTROGEN
ALUMINUM HYDROXIDE
ALUMINUM CARBONATE
NITRENDIPINE
MAGALDRATE
Habit Forming: No
Diet & Lifestyle Advise
1. Include food such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
2. Eat a healthy, well-balanced diet, which includes fruits and vegetables.
3.Foods rich in vitamins B and C and calcium are good for the gallbladder.
4.Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
5.Avoid high-fat, trans-fat and processed foods.
6.White bread, white pasta and sugars should be avoided.
7.Avoid tobacco and alcohol consumption.
Special Advise
Your doctor may recommend regular liver function tests to monitor liver function and the progress of treatment.
UBC 150 Tablet may rarely cause thinning and hair loss. If there is excessive hair loss, consult your doctor for further advice.
Disease/Condition Glossary
Primary biliary cholangitis: Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease caused by bile duct damage in the liver. Bile ducts are the small channels which carry the bile (digestive fluid) from the liver to the small intestine, where it breaks down fats and aids in its absorption. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.
Gallbladder stones: Gallbladder is a small organ located below the liver that stores bile and helps with digestion. Excess cholesterol in bile leads to the formation of gallstones. Gallstones can cause pain in the abdomen, dark urine and stools, indigestion, diarrhoea, nausea and vomiting.
Cystic fibrosis: It is a hereditary disease that affects the digestive system and lungs. In this condition, the body produces a thick and sticky fluid that obstructs the pancreas and clogs the lungs.
Safety Advice
Alcohol
Unsafe
Avoid consumption of alcohol while taking UBC 150 Tablet as it may cause increased dizziness and liver damage.
Pregnancy
Caution
UBC 150 Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Consult your doctor before taking UBC 150 Tablet ; your doctor will decide whether breastfeeding mothers can take UBC 150 Tablet or not.
Driving
Caution
UBC 150 Tablet does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
UBC 150 Tablet can be given to children with caution above 6 years and only if prescribed by the doctor.
STORAGE
Store in a cool and dry place away from sunlight
FAQs ABOUT UBC 150 TABLET
UBC 150 Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis.
UBC 150 Tablet works in decreasing the production of cholesterol and by dissolving the cholesterol in bile, thereby preventing the formation of gallstones. UBC 150 Tablet decreases the toxic levels of bile acids that accumulate in primary biliary cirrhosis.
Do not discontinue UBC 150 Tablet without consulting your doctor. To treat your condition effectually, continue taking UBC 150 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you have any difficulty taking UBC 150 Tablet .
Diarrhoea might be a side-effect of UBC 150 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Avoid taking aluminium-containing antacids along with UBC 150 Tablet , as they might interfere with its absorption. Maintain a gap of 2 hours between both.
UBC 150 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine). UBC 150 Tablet might increase the effect of immunosuppressants (cyclosporine). Cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Inform your doctor before taking UBC 150 Tablet with other medicines to avoid unpleasant side effects.
Oral contraceptives (oestrogen) might promote the formation of gallstones. Consult your doctor if you have any concerns regarding this, your doctor may advise other contraception methods.