Nexa L

Rabeprazole SODIUM (ENTERIC COATED) AND LEVOSULPIRIDE (SR) CAPSULES

MARKETER: Syngex Pharma Pvt Ltd

USES OF NEXA L TABLET
    • Acidity – Reduces excess stomach acid
    • Gastroesophageal Reflux Disease (GERD) – Controls acid reflux
    • Heartburn – Relieves burning sensation in chest
    • Indigestion (Dyspepsia) – Improves digestion
    • Gas & Bloating – Reduces heaviness and fullness
    • Nausea – Relieves feeling of vomiting
    • Functional Dyspepsia – Chronic stomach discomfort
    • Delayed Gastric Emptying – Helps stomach empty faster
HOW NEXA L TABLET WORKS

Nexa L works by a dual mechanism of action. Rabeprazole, a proton pump inhibitor, blocks the H⁺/K⁺ ATPase enzyme in the stomach lining, thereby reducing gastric acid secretion and relieving symptoms like acidity and heartburn. Levosulpiride, a prokinetic agent, enhances gastrointestinal motility by increasing acetylcholine activity, which helps in faster gastric emptying and reduces symptoms such as bloating and nausea. Together, these actions provide effective relief in conditions like Gastroesophageal Reflux Disease (GERD) and indigestion.

INTRODUCTION ABOUT NEXA L TABLET

NEXA-L capsule is an antacid and anti-reflux medicine. It is used for the treatment of gastrointestinal reflux disease (GERD). GERD is a condition where the stomach acid flows back to the food pipe along with the contents of the stomach, characterized by heartburn, chest pain, burning, pain and regurgitation of food or sour liquid due to irritation of the stomach. NEXA-L capsule has a combination of rabeprazole and levosulpiride as its active ingredients. This medicine lowers the acid secretion in the stomach and prevents the backflow of contents from the stomach to the food pipe. This medicine should be taken at least 30 minutes before meals. Along with this medicine, you need to make certain diet and lifestyle modifications like eating less oily and spicy food, avoiding alcohol and smoking and gentle regular exercise. This medicine should be taken as directed by the doctor and in doses and duration as prescribed. Before using the NEXA-L capsule, inform your doctor if you are pregnant, planning a pregnancy or breastfeeding about your detailed medical history.

Directions for Use – NEXA-L Capsule
  • Take NEXA-L capsule exactly as prescribed by your doctor.
  • It is usually advised to take the capsule once daily, preferably before meals (before breakfast) for better effectiveness.
  • Swallow the capsule whole with a glass of water; do not crush, chew, or open it.
  • Take the medicine at the same time each day to maintain consistent results.
  • Do not exceed the recommended dose or duration without consulting your doctor.
  • If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed one—do not double the dose.
Contraindications & Side Effects
Contraindications:
  • Hypersensitivity to rabeprazole or levosulpiride
    → Patients with known allergy to any component of Nexa L should avoid its use, as it may cause allergic reactions such as rash, swelling, or breathing difficulty.
  • History of seizure disorders (fits)
    → Levosulpiride may increase the risk of seizures, therefore it should not be used in patients with a history of epilepsy or fits.
  • Patients with Parkinson’s Disease
    → Levosulpiride can worsen symptoms like tremors and muscle rigidity in such patients.
  • Pregnancy
    → The safety of this medicine during pregnancy is not well established; hence, it is contraindicated unless prescribed by a doctor.
  • Breastfeeding
    → The drug may pass into breast milk and could affect the infant, so it should be avoided.
Adverse Effects:
  • Headache
    → Mild to moderate headache may occur due to changes in body response to the medicine.
  • Dizziness
    → Patients may feel lightheaded; caution is advised while driving or operating machinery.
  • Diarrhoea
    → Increased bowel movements may occur due to changes in gastrointestinal activity.
  • Abdominal (stomach) discomfort
    → Some patients may experience pain, cramps, or uneasiness in the stomach.
  • Back pain
    → Occasional muscle or back pain has been reported during use.
HOW TO MANAGE SIDE EFFECTS

NEXA-L (rabeprazole + levosulpiride) is generally well tolerated, but some people may experience mild side effects. Here’s how to manage them:

1. Headache

  • Stay well hydrated and rest properly
  • Avoid stress and screen overuse
  • If needed, take a mild pain reliever only after consulting a doctor

2. Nausea or Vomiting

  • Take the medicine before meals as advised
  • Eat light, non-spicy food
  • Avoid oily and heavy meals

3. Diarrhea

  • Drink plenty of fluids (water, ORS) to prevent dehydration
  • Avoid junk or contaminated food
  • If it continues for more than 2–3 days, consult a doctor

4. Constipation

  • Increase fiber intake (fruits, vegetables, whole grains)
  • Drink enough water
  • Stay physically active

5. Dizziness or Drowsiness

  • Avoid driving or operating machinery
  • Get up slowly from sitting/lying position
  • Avoid alcohol

6. Dry Mouth

  • Drink water frequently
  • Chew sugar-free gum or suck on lozenges

When to Consult a Doctor

  • If side effects are severe or persistent
  • If you experience unusual symptoms like muscle stiffness, tremors, or irregular heartbeat
Warnings & Precautions
  • Use this medicine only under the supervision of a doctor.
  • Inform your doctor if you have liver or kidney problems before taking it.
  • Avoid use if you have a history of fits (seizures) or neurological disorders.
  • Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
  • Avoid alcohol, as it may increase dizziness and drowsiness.
  • Do not drive or operate machinery if you feel sleepy or dizzy after taking it.
  • Long-term use should be avoided unless prescribed, as it may cause nutritional deficiencies or other complications.
  • Inform your doctor about all other medicines you are taking to avoid drug interactions